At Paragon RX Clinical, we partner with a local advanced imaging center equipped with state-of-the-art diagnostic technology to support early detection, disease monitoring, and protocol-specific imaging endpoints across a wide range of therapeutic areas. While the imaging equipment is not housed onsite, our close collaboration ensures seamless scheduling, high-quality imaging, and rapid turnaround to meet study demands. Below is a comprehensive list of the imaging capabilities available through our partnership and how each contributes to the success of our clinical research trials.
1. MRI Scanner – High-Resolution Brain and Tissue Imaging
- Provides exceptional soft tissue contrast for neurology, musculoskeletal, and oncology studies
- Supports Alzheimer’s disease, multiple sclerosis, and brain cancer research
- Enhances sponsor confidence through quality imaging biomarkers and volumetric analysis
2. CT Scanner – Rapid Cross-Sectional Imaging
- Delivers fast, accurate anatomical imaging for cardiovascular, GI, and oncology trials
- Enables baseline, follow-up, and tumor response assessments in cancer studies
- Essential for lung cancer screening, colorectal imaging, and metastasis tracking
3. DEXA Scan – Bone Density and Body Composition
- Supports metabolic disease trials, including obesity and osteoporosis studies
- Offers precise lean/fat mass measurements and BMD tracking over time
- Non-invasive, quick, and sponsor-preferred for body composition endpoints
4. Ultrasound with Doppler – Real-Time Soft Tissue and Vascular Imaging
- Enables real-time procedural guidance for liver biopsies and targeted injections
- Ideal for hepatology, gynecology, and cardiovascular protocols
- Portable and non-invasive—perfect for diverse populations and longitudinal follow-up
5. Digital X-ray – Fast and Efficient Diagnostic Imaging
- Commonly used for eligibility screening in orthopedic and respiratory trials
- Low-radiation, quick turnaround for same-day diagnostic decisions
- Essential in early-phase studies for detecting bone fractures, lung abnormalities, and joint changes
6. PET/CT Access – Advanced Metabolic and Oncology Imaging
- Enables precise functional and anatomical imaging in one session
- Valuable for immunotherapy, oncology, and CNS studies requiring biomarker data
- Often used for disease staging and monitoring treatment response
7. Echosens FibroScan® – Non-Invasive Liver Fibrosis and Steatosis Assessment
- Ideal for screening, patient stratification, and follow-up assessments in liver studies
- Enhances patient comfort and enrollment by reducing reliance on liver biopsy
- Widely accepted by sponsors and regulatory agencies as a validated surrogate endpoint for NASH and NAFLD trials
8. Liver-Specific MRI with Quantitative Imaging Software – Precision Imaging for Liver Disease Trials
- Equipped with advanced liver-specific MRI and imaging software, ideal for clinical trials requiring non-invasive liver assessments
- Enables quantitative analysis of liver fat, fibrosis, and inflammation—critical for modern endpoints in hepatology and metabolic studies
Clinical Trial Indications Supported by Liver-Specific MRI:
- NASH (Nonalcoholic Steatohepatitis): Detects liver inflammation and fibrosis without biopsy, ideal for longitudinal tracking in therapeutic trials
- NAFLD (Nonalcoholic Fatty Liver Disease): Accurately quantifies liver fat content, enabling early intervention and lifestyle-modification trials
- MASH (Metabolic Dysfunction–Associated Steatohepatitis): Offers comprehensive liver and metabolic imaging to align with evolving diagnostic criteria
- Chronic Hepatitis B & C: Monitors liver damage progression and treatment response in antiviral drug studies
- Liver Fibrosis & Cirrhosis: Uses MR elastography and T1/T2 mapping to non-invasively stage fibrosis
- Alcohol-Related Liver Disease (ALD): Evaluates steatosis, inflammation, and fibrosis to support pharmacologic and behavioral research
